Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.36 |
| ▸ | CA1 | P00915 | 9/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670948 | 0.98 | CA2 (0.37) | CA2CA1CA5ACA9MMP1 | |
| SCHEMBL2482919 | 0.84 | RORA (0.40) | CA2CA1CA9MMP1MMP2 | |
| SCHEMBL3914557 | 0.83 | CA2 (0.36) | CA2CA1CA5ACA9MMP1 | |
| Benzenethiol SCHEMBL29745974 | 0.83 | CA2 (0.39) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL4392561 | 0.83 | HSD11B1 (0.41) | CA2CA1CA9MMP1MMP2 | |
| Trifluoromethanesulfonic Acid SCHEMBL6248784 | 0.82 | CA2 (0.42) | CA2CA1CA5ACA9MMP1 | |
| SCHEMBL4399560 | 0.81 | HSD11B1 (0.40) | CA2CA1CA9MMP1MMP2 | |
| Trifluoromethanesulfonic Acid SCHEMBL1455936 | 0.80 | CA2 (0.41) | CA2CA1CA5ACA9MMP1 | |
| SCHEMBL29670941 | 0.79 | CA2 (0.35) | CA2CA1CA5ACA9MMP1 | |
| SCHEMBL2902138 | 0.78 | CA2 (0.33) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696216-B2 | A PHOTO ACID GENERATOR USED IN GENERATING AN ACID FOR CHEMICALLY CLEAVING ACID SENSITIVE SIDE CHAINS OF A CHEMICALLY AMPLIFIED BASE POLYMER CONTAINS A SULFONIUM OR IODONIUM SALT CONTAINING ATLEAST ONE THIOPHENE RING | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2004-02-24 | — | — | US | disclosed |
| US-20030008230-A1 | Thiophene-containing photo acid generators for photolithography | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-01-09 | — | — | US | disclosed |
| WO-2003003120-A1 | THIOPHENE-CONTAINING PHOTO ACID GENERATORS FOR PHOTOLITHOGRAPHY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2003-01-09 | — | — | WO | disclosed |