Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186336 | 0.87 | CA1 (0.32) | CA1CA2HPGDGABRA1GABRG2 | |
| SCHEMBL7333093 | 0.81 | CA12 (0.41) | CA1CA2CA12CA4CA7 | |
| SCHEMBL30584471 | 0.81 | CA12 (0.41) | CA1CA2CA12CA4CA7 | |
| SCHEMBL9303081 | 0.77 | CA1 (0.60) | CA1CA2CA12CA4CA7 | |
| SCHEMBL6909918 | 0.76 | GABRA1 (0.41) | CA1CA2HPGDGABRA1GABRG2 | |
| SCHEMBL6745346 | 0.74 | TAAR1 (0.47) | CA1CA2CA12CA9CA14 | |
| SCHEMBL29734610 | 0.73 | CYP1A2 (0.41) | CA1CA2ALDH1A1HPGDGABRA1 | |
| SCHEMBL5698312 | 0.73 | P2RX7 (0.36) | CA1CA2HPGDGABRA1GABRG2 | |
| SCHEMBL4408091 | 0.70 | PPARG (0.38) | ALDH1A1MAPTHPGDHTT | |
| SCHEMBL5344889 | 0.69 | CA1 (0.35) | CA1CA2CA12CA9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063951-A1 | Alkaloid halide salts of swainsonine and methods of use | GLYCODESIGN HOLDINGS LTD. (CA) | 2004-04-01 | — | — | US | disclosed |
| US-20030105326-A1 | Alkaloid halide salts of swainsonine and methods of use | DENNIS JAMES W (CA) | 2003-06-05 | — | — | US | disclosed |
| EP-1264832-A1 | Alkaloid halide salts of swainsonine and methods of use | Glycodesign Inc. (CA) | 2002-12-11 | — | — | EP | disclosed |
| EP-0975632-B1 | ALKALOID HALIDE SALTS OF SWAINSONINE AND METHODS OF USE | GLYCODESIGN INC (CA) | 2002-10-16 | — | — | EP | disclosed |
| US-6395745-B1 | STABLE, CRYSTAL STRUCTURE; PLANT EXTRACT | GLYCODESIGN, INC. (CA) | 2002-05-28 | — | — | US | disclosed |
| EP-0975632-A1 | ALKALOID HALIDE SALTS OF SWAINSONINE AND METHODS OF USE | Glycodesign Inc. (CA) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046602-A1 | ALKALOID HALIDE SALTS OF SWAINSONINE AND METHODS OF USE | GLYCODESIGN INC. (CA) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105326-A1 | Alkaloid halide salts of swainsonine and methods of use | SLC6A12, PWWP2B, WNK2 | CA1 477/4885CA2 1032/4885CA12 373/4885 |
| US-20040063951-A1 | Alkaloid halide salts of swainsonine and methods of use | SLC6A12, TUBB3, HNMT | CA1 388/4885CA2 1110/4885CA12 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.