Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746753 | 0.88 | PTGS2 (0.45) | CASP1PTGS2 | |
| SCHEMBL6745114 | 0.87 | SDHB (0.38) | CASP1PTGS2 | |
| SCHEMBL6746033 | 0.86 | CYP11B1 (0.38) | CASP1PTGS2 | |
| SCHEMBL6749937 | 0.85 | PTGS2 (0.36) | CASP1PTGS2 | |
| SCHEMBL6746730 | 0.83 | PTGS2 (0.38) | CASP1PTGS2 | |
| SCHEMBL6743712 | 0.83 | PTGS2 (0.44) | PTGS2 | |
| SCHEMBL6744935 | 0.83 | PTGS2 (0.36) | CASP1PTGS2 | |
| SCHEMBL6745120 | 0.83 | ACLY (0.35) | CASP1PTGS2 | |
| SCHEMBL6750091 | 0.83 | CASP1 (0.35) | CASP1PTGS2 | |
| SCHEMBL6749879 | 0.83 | CASP1 (0.40) | CASP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |