Sugi Predict

Sugi Predict / Compounds / SCHEMBL6746709

SCHEMBL6746709

SCHEMBL6746709

CCOC(OCC)[SiH2]c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ CYP1A1 P04798 2/20 0.37
▸ CYP1B1 Q16678 2/20 0.37
▸ CYP1A2 P05177 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ CYP3A4 P08684 2/20 0.37
▸ HPGD P15428 2/20 0.37
▸ TSHR P16473 2/20 0.37
▸ HSD17B10 Q99714 2/20 0.37
▸ ERBB2 P04626 1/20 0.33
▸ FYN P06241 1/20 0.33
▸ MAOA P21397 1/20 0.33
▸ ACHE P22303 1/20 0.33
▸ AHR P35869 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6744747 0.88 CYP1A2 (0.33) CYP1A2ALDH1A1HPGDHSD17B10ERBB2
SCHEMBL6751469 0.81 CYP1A2 (0.40) TDP1KDM4ECYP1A1CYP1B1CYP1A2
SCHEMBL6748671 0.81 CYP1A2 (0.41) TDP1KDM4ECYP1A1CYP1B1CYP1A2
SCHEMBL6749503 0.80 CYP2A6 (0.35) TDP1KDM4ECYP1A2ALDH1A1CYP3A4
SCHEMBL6749460 0.78 ALDH1A1 (0.41) TDP1KDM4ECYP1A1CYP1B1CYP1A2
SCHEMBL707975 0.73 THRB (0.35) L3MBTL1
SCHEMBL27888648 0.72 ACHE (0.38) TDP1CYP1A2ALDH1A1CYP3A4HPGD
SCHEMBL208072 0.72 L3MBTL1 (0.41) MEN1KMT2AL3MBTL1
SCHEMBL6748380 0.72 CYP1A2 (0.39) TDP1CYP1A2ALDH1A1CYP3A4HPGD
SCHEMBL6746636 0.70 CYP1A2 (0.32) CYP1A2ALDH1A1HPGDHSD17B10ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 — — US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 — — EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 — — US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 — — US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 TDP1 4084/4885KDM4E 296/4885CYP1A1 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.