SCHEMBL6749503

SCHEMBL6749503

CCOC(OCC)[SiH2]c1ccc2cc3cc4ccccc4cc3cc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.35
CYP1A2 P05177 2/20 0.35
TDP1 Q9NUW8 3/20 0.34
GAA P10253 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 2/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HBB P68871 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6751478 0.81 CYP2A6 (0.39) CYP2A6CYP1A2TDP1ALDH1A1CYP3A4
SCHEMBL6746709 0.80 TDP1 (0.39) CYP1A2TDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL6748714 0.78 L3MBTL1 (0.32) L3MBTL1
SCHEMBL707975 0.78 THRB (0.35) L3MBTL1LMNA
SCHEMBL6746797 0.76 NQO1 (0.33) GAAALDH1A1KDM4E
SCHEMBL208072 0.76 L3MBTL1 (0.41) L3MBTL1MEN1NPC1LMNAKMT2A
SCHEMBL6751439 0.73 NR1I2 (0.34) GAAL3MBTL1ALDH1A1HIF1AHSD17B10
SCHEMBL27888648 0.72 ACHE (0.38) CYP1A2TDP1L3MBTL1MAPK1ALDH1A1
SCHEMBL6744747 0.72 CYP1A2 (0.33) CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL6749459 0.71 ALDH1A1 (0.38) CYP1A2TDP1L3MBTL1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 CYP2A6 4100/4885CYP1A2 2466/4885TDP1 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.