Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 4/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744770 | 0.88 | KIF11 (0.43) | LMNAARFEN1ALOX5APMAOB | |
| SCHEMBL6729590 | 0.86 | FEN1 (0.47) | LMNAARFEN1ALOX5APMAOB | |
| SCHEMBL6744241 | 0.85 | FEN1 (0.43) | FEN1ALOX5APMAOBCA1CA2 | |
| SCHEMBL6835049 | 0.84 | LMNA (0.42) | LMNAARMAOBADORA2AADORA1 | |
| SCHEMBL6743148 | 0.84 | PTGS2 (0.51) | FEN1ALOX5APCA1CA2GAA | |
| SCHEMBL6743007 | 0.83 | FEN1 (0.41) | FEN1ALOX5APADORA1PTGES2CA1 | |
| SCHEMBL6747351 | 0.83 | FEN1 (0.41) | FEN1ALOX5APMAOBCA1CA2 | |
| SCHEMBL6746016 | 0.83 | RORB (0.43) | FEN1MAOBADORA2AADORA1KCNA5 | |
| SCHEMBL6749869 | 0.83 | DHODH (0.42) | FEN1ADORA2AADORA1KCNA5KCNH2 | |
| SCHEMBL6746754 | 0.83 | FEN1 (0.44) | FEN1ALOX5APMAOBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |