Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035638 | 0.73 | SIGMAR1 (0.61) | SIGMAR1ALDH1A1NPC1SMN1; SMN2HPGD | |
| SCHEMBL14800103 | 0.73 | SSTR4 (0.48) | RAB9ALMNANPC1SMN1; SMN2SSTR4 | |
| SCHEMBL1476176 | 0.70 | SLC6A2 (0.48) | SIGMAR1RAB9ASLC6A2SLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1474677 | 0.69 | SLC6A2 (0.47) | SIGMAR1RAB9ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL11861949 | 0.67 | HRH1 (0.53) | SIGMAR1SLC6A2SLC6A3LMNATAAR1 | |
| SCHEMBL5310845 | 0.67 | HRH1 (0.43) | SLC6A2SLC6A3LMNASMN1; SMN2 | |
| SCHEMBL9978781 | 0.67 | GBA1 (0.50) | SIGMAR1SLC6A2SLC6A3LMNATAAR1 | |
| Hydrochloric Acid SCHEMBL11843236 | 0.66 | HRH1 (0.51) | SIGMAR1SLC6A2SLC6A3LMNATAAR1 | |
| Trifluoroacetic Acid SCHEMBL5037785 | 0.66 | SLC6A2 (0.46) | SIGMAR1KDM4ESLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL12748513 | 0.66 | SLC6A2 (0.43) | SIGMAR1SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122049-A1 | Novel piperidine derivatives as modulators of chemokine receptor | ASTRAZENECA AB (SE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122049-A1 | Novel piperidine derivatives as modulators of chemokine receptor | CCR5, CCR2, CXCR1 | SIGMAR1 127/4885RAB9A 708/4885KDM4E 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.