Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365385 | 0.85 | SIGMAR1 (0.50) | KIF11TSHRSIGMAR1CYP3A4KCNH2 | |
| SCHEMBL532850 | 0.82 | KIF11 (0.61) | KIF11CYP3A4KCNH2CYP2D6CYP2C9 | |
| SCHEMBL15051981 | 0.80 | KIF11 (0.59) | KIF11CYP3A4KCNH2CYP2D6CYP2C9 | |
| Water SCHEMBL28757871 | 0.80 | KIF11 (0.59) | KIF11CYP3A4KCNH2CYP2D6CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL4606388 | 0.80 | KIF11 (0.59) | KIF11CYP3A4KCNH2CYP2D6CYP2C9 | |
| Diethylaniline SCHEMBL393151 | 0.76 | TSHR (0.39) | KIF11TSHRCNR2SIGMAR1MEN1 | |
| Pyrene SCHEMBL8422504 | 0.76 | SIGMAR1 (0.42) | KIF11TSHRSIGMAR1CYP3A4KCNH2 | |
| SCHEMBL810137 | 0.75 | KIF11 (0.57) | KIF11SIGMAR1CYP3A4KCNH2CYP2D6 | |
| Tetrabuthylammonium SCHEMBL22518565 | 0.74 | KIF11 (0.44) | KIF11CYP3A4KCNH2CYP2D6CYP2C9 | |
| Diethylaniline SCHEMBL27763632 | 0.74 | TSHR (0.64) | TSHRCNR2CYP3A4MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696532-B2 | OLEFIN POLYMERIZATION CATALYSTS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2004-02-24 | — | — | US | disclosed |
| US-6686491-B2 | ALUMINUM PHOSPHINIMINE COMPLEXES AND METHOD OF MAKING; SOLUTION POLYMERIZATION AND SLURRY POLYMERIZATION OF ETHYLENE HOMO- AND CO-POLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2004-02-03 | — | — | US | disclosed |
| US-20030114696-A1 | Phosphinimine methanide transition metal catalysts | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA | 2003-06-19 | — | — | US | disclosed |
| US-20030028041-A1 | Novel aluminum complexes for olefin polymerization | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA | 2003-02-06 | — | — | US | disclosed |
| US-6492474-B2 | ALUMINUM PHOSPHINIMINE COMPLEXES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2002-12-10 | — | — | US | disclosed |
| US-6476245-B1 | Phosphinimine methanide transition metal catalysts | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2002-11-05 | — | — | US | disclosed |
| US-6444834-B1 | COORDINATION CATALYSTS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2002-09-03 | — | — | US | disclosed |
| US-6313331-B1 | Carbene transition metal catalysts | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2001-11-06 | — | — | US | disclosed |
| US-20010018534-A1 | Aluminum complexes for olefin polymerization | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA | 2001-08-30 | — | — | US | disclosed |
| US-6235919-B1 | COORDINATION CATALYSTS OF ALUMINUM AND PHOSPHINIMINES FOR POLYMERIZATION OF OLEFINS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2001-05-22 | — | — | US | disclosed |
| US-6060568-A | Carbene transition metal catalysts | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2000-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028041-A1 | Novel aluminum complexes for olefin polymerization | ALOX12, ALOX15B, ALOX5 | KIF11 3533/4885TSHR 4836/4885CNR2 2824/4885 |
| US-20030114696-A1 | Phosphinimine methanide transition metal catalysts | TIMM9, TIMM13, TIMM10 | KIF11 928/4885TSHR 4219/4885CNR2 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.