Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748554 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBLMNAL3MBTL1 | |
| SCHEMBL15085214 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL28220083 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL29954953 | 0.71 | KDM4E (0.52) | ALDH1A1KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL2343158 | 0.71 | KDM4E (0.52) | ALDH1A1KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL22443301 | 0.71 | L3MBTL1 (0.52) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9509638 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9505790 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9737954 | 0.68 | L3MBTL1 (0.47) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL15082789 | 0.68 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296873-B1 | DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5004812-A | Phenyl-pyridyl-indole Intermediates For Desensitizing Dyes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-02 | — | — | US | disclosed |
| US-4927933-A | PHOTOGRAPHIC FILMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4839271-A | SENSITIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-13 | — | — | US | disclosed |