SCHEMBL45712

SCHEMBL45712

CC(C)(C)c1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 1/20 0.52
PPARG P37231 7/20 0.46
PPARA Q07869 2/20 0.44
PMM2 O15305 1/20 0.42
MPI P34949 1/20 0.42
PHOSPHO1 Q8TCT1 1/20 0.42
KIF11 P52732 3/20 0.39
NR1H4 Q96RI1 1/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.38
MAPK1 P28482 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
DNM1 Q05193 1/20 0.38
PGR P06401 1/20 0.38
RORA P35398 1/20 0.38
RORC P51449 1/20 0.38
RORB Q92753 1/20 0.38
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745992 1.00 KDM4E (0.52) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL27272675 0.95 KDM4E (0.47) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL27050245 0.94 KDM4E (0.46) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL25708817 0.93 KDM4E (0.52) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL674884 0.93 KDM4E (0.59) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL29875801 0.93 KDM4E (0.59) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL8739914 0.92 KDM4E (0.56) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL8739923 0.92 KDM4E (0.56) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL15746001 0.92 KDM4E (0.56) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL16940887 0.92 KDM4E (0.56) KDM4EL3MBTL1ATMPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-20220336752-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element UDC IRELAND LIMITED (IE) 2022-10-20 US disclosed
US-10944061-B2 Organic electroluminescent element and compound UDC IRELAND LIMITED (IE) 2021-03-09 US disclosed
US-10644243-B2 N-phenyl triscarbazole NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-05-05 US disclosed
US-20190259955-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT-EMITTING MATERIAL THEREFOR, LIGHT EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE UDC IRELAND LTD (IE) 2019-08-22 US disclosed
US-20190259964-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM SOLVAY SA (BE) 2019-08-22 US disclosed
US-10388903-B2 Charge-transporting material, organic electroluminescent element, and light-emitting device, display device and illumination device characterised by using said element UDC IRELAND LIMITED (IE) 2019-08-20 US disclosed
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT UDC IRELAND LTD (IE) 2018-04-12 US disclosed
US-20180069179-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LTD (IE) 2018-03-08 US disclosed
EP-2461390-A1 ORGANIC ELECTROLUMINESCENT ELEMENT FUJIFILM Corporation (JP) 2012-06-06 EP disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
WO-2012025510-A1 N-PHENYL TRISCARBAZOLE SOLVAY SA (BE) 2012-03-01 WO disclosed
WO-2011024733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171418-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 KDM4E 2299/4885L3MBTL1 963/4885ATM 3234/4885
US-10388903-B2 Charge-transporting material, organic electroluminescent element, and light-emitting device, display device and illumination device characterised by using said element L1CAM, EPB41L2, EPB41 KDM4E 3370/4885L3MBTL1 252/4885ATM 4499/4885
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE SLC26A3, SLC43A3, SLCO2A1 KDM4E 4092/4885L3MBTL1 1106/4885ATM 3592/4885
US-10944061-B2 Organic electroluminescent element and compound POU2F2, DDT, LEF1 KDM4E 1349/4885L3MBTL1 212/4885ATM 3192/4885
US-20180069179-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element L1CAM, RER1, H1-0 KDM4E 3994/4885L3MBTL1 518/4885ATM 3975/4885
US-20220336752-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element L1CAM, NR2E3, OR10J3 KDM4E 863/4885L3MBTL1 156/4885ATM 2619/4885
US-20180102483-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, USED IN THE SAME, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE AND ILLUMINATION DEVICE, USING THE ELEMENT RPS10, RPS20, RPS19 KDM4E 1007/4885L3MBTL1 377/4885ATM 2168/4885
US-10644243-B2 N-phenyl triscarbazole RB1, LBR, NR1I2 KDM4E 1474/4885L3MBTL1 977/4885ATM 2980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.