Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745201 | 0.89 | ACLY (0.43) | NR1H2NR1H3PTGS2ACLY | |
| SCHEMBL6743464 | 0.88 | PTGS2 (0.38) | NR1H2NR1H3PTGS2ACLY | |
| SCHEMBL6747140 | 0.87 | PTGS2 (0.36) | NR1H2NR1H3PTGS2ACLY | |
| SCHEMBL6746862 | 0.87 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL6746680 | 0.86 | NR1H2 (0.36) | NR1H2NR1H3PTGS2ACLYKAT6A | |
| SCHEMBL6747114 | 0.85 | RAB9A (0.40) | NR1H2NR1H3PTGS2ACLY | |
| SCHEMBL6746733 | 0.84 | PTGS2 (0.34) | NR1H2NR1H3PTGS2ACLY | |
| SCHEMBL6746771 | 0.83 | NR1H2 (0.41) | NR1H2NR1H3PTGS2 | |
| SCHEMBL6746727 | 0.83 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL6746140 | 0.82 | EPAS1 (0.37) | NR1H2NR1H3ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |