Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | ARNT | P27540 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746380 | 0.87 | PTGS2 (0.39) | ACLYPGR | |
| SCHEMBL6743464 | 0.84 | PTGS2 (0.38) | ACLYNR1H2NR1H3SLC6A9 | |
| SCHEMBL6746680 | 0.83 | NR1H2 (0.36) | ACLYNR1H2NR1H3CLK4 | |
| SCHEMBL6745201 | 0.83 | ACLY (0.43) | ACLYNR1H2NR1H3 | |
| SCHEMBL6747114 | 0.82 | RAB9A (0.40) | ACLYPGRNR1H2NR1H3 | |
| SCHEMBL6749677 | 0.82 | NR1H2 (0.36) | ACLYNR1H2NR1H3 | |
| SCHEMBL6747126 | 0.81 | ARNT (0.39) | EPAS1ARNTGABRG2GABRB3GABRA5 | |
| SCHEMBL6746666 | 0.81 | PTGS2 (0.36) | EPAS1PGR | |
| SCHEMBL6747428 | 0.81 | PTGS2 (0.36) | EPAS1PIK3CA | |
| SCHEMBL6746771 | 0.81 | NR1H2 (0.41) | NR1H2NR1H3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |