Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749515 | 0.81 | AKT1 (0.47) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL6747496 | 0.73 | TP53 (0.33) | HTR1AHTR7HTR2AALDH1A1L3MBTL1 | |
| SCHEMBL7095382 | 0.73 | HTR1A (0.58) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL7094852 | 0.70 | ALDH1A1 (0.79) | ALDH1A1MBTD1L3MBTL1LMNAHPGD | |
| SCHEMBL7140092 | 0.69 | MTNR1A (0.39) | HTR1AHTR2ADRD2DRD4ADRA1A | |
| SCHEMBL7094855 | 0.69 | L3MBTL1 (0.59) | HTR1AALDH1A1MBTD1L3MBTL1LMNA | |
| SCHEMBL17368827 | 0.69 | ALDH1A1 (0.49) | HTR1AHTR7HTR2ASLC6A4HTR2B | |
| SCHEMBL7097551 | 0.69 | ALDH1A1 (0.77) | ALDH1A1MBTD1L3MBTL1LMNAHTT | |
| SCHEMBL7095193 | 0.69 | ALDH1A1 (0.77) | ALDH1A1MBTD1L3MBTL1LMNAHTT | |
| SCHEMBL7093365 | 0.69 | ALDH1A1 (0.77) | ALDH1A1MBTD1L3MBTL1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | HTR1A 1339/4885HTR7 1009/4885HTR2A 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.