Sugi Predict

Sugi Predict / Compounds / SCHEMBL6750145

SCHEMBL6750145

SCHEMBL6750145

COC(=O)CCCC#CCC#CCBr

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.48
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ RECQL P46063 2/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ ALOX12 P18054 1/20 0.43
▸ PTPN7 P35236 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ MCL1 Q07820 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ PPARG P37231 4/20 0.37
▸ PPARA Q07869 4/20 0.37
▸ LMNA P02545 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9975554 1.00 TSHR (0.48) TSHRMEN1KMT2ARECQLTDP1
SCHEMBL317846 0.94 TSHR (0.54) TSHRMEN1KMT2ARECQLTDP1
SCHEMBL12485479 0.93 TSHR (0.45) TSHRMEN1KMT2ARECQLTDP1
SCHEMBL19877940 0.89 TSHR (0.44) TSHRMEN1KMT2ARECQLTDP1
SCHEMBL19878386 0.89 TSHR (0.44) TSHRMEN1KMT2ARECQLTDP1
SCHEMBL11282688 0.89 TSHR (0.52) TSHRMEN1KMT2ARECQLALDH1A1
SCHEMBL18092654 0.84 TSHR (0.50) TSHRMEN1KMT2ARECQLTDP1
SCHEMBL6744982 0.84 TSHR (0.50) TSHRMEN1KMT2ARECQLTDP1
SCHEMBL9975548 0.84 TSHR (0.50) TSHRMEN1KMT2ARECQLTDP1
SCHEMBL19890840 0.84 TSHR (0.50) TSHRMEN1KMT2ARECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001783-B2 Synthesis and use of ω-hydroxylated polyunsaturated fatty acids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-05-11 — — US disclosed
US-11001783-B2 Synthesis and use of ω-hydroxylated polyunsaturated fatty acids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-05-11 — — US disclosed
US-20200332224-A1 SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-10-22 — — US disclosed
US-20200332224-A1 SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-10-22 — — US disclosed
US-10689595-B2 Synthesis and use of omega-hydroxylated polyunsaturated fatty acids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-06-23 — — US disclosed
US-10689595-B2 Synthesis and use of omega-hydroxylated polyunsaturated fatty acids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-06-23 — — US disclosed
US-20190270950-A1 SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-09-05 — — US disclosed
US-20190270950-A1 SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-09-05 — — US disclosed
WO-2018035208-A1 SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-02-22 — — WO disclosed
WO-2018035208-A1 SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-02-22 — — WO disclosed
WO-2016160544-A1 LIPID PROBES AND USES THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2016-10-06 — — WO disclosed
US-20160282369-A1 LIPID PROBES AND USES THEREOF THE SCRIPPS RESEARCH INSTITUTE 2016-09-29 — — US disclosed
US-20160282369-A1 LIPID PROBES AND USES THEREOF THE SCRIPPS RESEARCH INSTITUTE 2016-09-29 — — US disclosed
US-8202893-B2 Cannabinergic lipid ligands UNIVERSITY OF CONNECTICUT (US) 2012-06-19 — — US disclosed
US-20090163557-A1 Cannabinergic Lipid Ligands NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2009-06-25 — — US disclosed
US-20040122089-A1 Analogs of andandamide and arvanil have been found to act at receptors; are useful in pain management, used as anti-proliferative/anti-tumor agents, vasodilators, and in other applications VIRGINIA COMMONWEALTH UNIVERSITY 2004-06-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001783-B2 Synthesis and use of ω-hydroxylated polyunsaturated fatty acids ALOX15, ALOX5, ALOX12 TSHR 1558/4885MEN1 2236/4885KMT2A 2795/4885
US-10689595-B2 Synthesis and use of omega-hydroxylated polyunsaturated fatty acids ALOX15, ALOX5, ALOX12 TSHR 1532/4885MEN1 2168/4885KMT2A 2655/4885
US-20190270950-A1 SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS ALOX15, ALOX5, ALOX12 TSHR 1532/4885MEN1 2168/4885KMT2A 2655/4885
US-20200332224-A1 SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS ALOX15, ALOX5, ALOX12 TSHR 1532/4885MEN1 2168/4885KMT2A 2655/4885
US-20090163557-A1 Cannabinergic Lipid Ligands FAAH, FAAH2, CNR2 TSHR 885/4885MEN1 4518/4885KMT2A 3660/4885
US-20040122089-A1 Analogs of andandamide and arvanil have been found to act at receptors; are useful in pain management, used as anti-proliferative/anti-tumor agents, vasodilators, and in other applications CNR1, AVPR1A, OPRL1 TSHR 3478/4885MEN1 4164/4885KMT2A 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.