Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9975552 | 1.00 | TSHR (0.50) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL9975548 | 1.00 | TSHR (0.50) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL12484115 | 0.95 | TSHR (0.48) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL659218 | 0.94 | TSHR (0.56) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL12484150 | 0.93 | TSHR (0.47) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL12484913 | 0.93 | TSHR (0.47) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL9975545 | 0.89 | TSHR (0.50) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL19878362 | 0.89 | TSHR (0.50) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL18092654 | 0.89 | TSHR (0.50) | TSHRMEN1KMT2ARECQLTDP1 | |
| SCHEMBL6748258 | 0.89 | TSHR (0.50) | TSHRMEN1KMT2ARECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001783-B2 | Synthesis and use of ω-hydroxylated polyunsaturated fatty acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200332224-A1 | SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-10-22 | — | — | US | disclosed |
| US-10689595-B2 | Synthesis and use of omega-hydroxylated polyunsaturated fatty acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-06-23 | — | — | US | disclosed |
| US-10689595-B2 | Synthesis and use of omega-hydroxylated polyunsaturated fatty acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190270950-A1 | SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-09-05 | — | — | US | disclosed |
| US-20190270950-A1 | SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-09-05 | — | — | US | disclosed |
| WO-2018035208-A1 | SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-22 | — | — | WO | disclosed |
| WO-2018035208-A1 | SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-22 | — | — | WO | disclosed |
| US-8202893-B2 | Cannabinergic lipid ligands | UNIVERSITY OF CONNECTICUT (US) | 2012-06-19 | — | — | US | disclosed |
| US-20090163557-A1 | Cannabinergic Lipid Ligands | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-06-25 | — | — | US | disclosed |
| US-20040122089-A1 | Analogs of andandamide and arvanil have been found to act at receptors; are useful in pain management, used as anti-proliferative/anti-tumor agents, vasodilators, and in other applications | VIRGINIA COMMONWEALTH UNIVERSITY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11001783-B2 | Synthesis and use of ω-hydroxylated polyunsaturated fatty acids | ALOX15, ALOX5, ALOX12 | TSHR 1558/4885MEN1 2236/4885KMT2A 2795/4885 |
| US-10689595-B2 | Synthesis and use of omega-hydroxylated polyunsaturated fatty acids | ALOX15, ALOX5, ALOX12 | TSHR 1532/4885MEN1 2168/4885KMT2A 2655/4885 |
| US-20190270950-A1 | SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS | ALOX15, ALOX5, ALOX12 | TSHR 1532/4885MEN1 2168/4885KMT2A 2655/4885 |
| US-20200332224-A1 | SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS | ALOX15, ALOX5, ALOX12 | TSHR 1532/4885MEN1 2168/4885KMT2A 2655/4885 |
| US-20090163557-A1 | Cannabinergic Lipid Ligands | FAAH, FAAH2, CNR2 | TSHR 885/4885MEN1 4518/4885KMT2A 3660/4885 |
| US-20040122089-A1 | Analogs of andandamide and arvanil have been found to act at receptors; are useful in pain management, used as anti-proliferative/anti-tumor agents, vasodilators, and in other applications | CNR1, AVPR1A, OPRL1 | TSHR 3478/4885MEN1 4164/4885KMT2A 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.