Water

Water

SCHEMBL675388

C=CCP.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26908 0.95
SCHEMBL10948468 0.95
Phosphine SCHEMBL7553985 0.90
SCHEMBL10749779 0.90
Hydrochloric Acid SCHEMBL8653131 0.90
Bromide SCHEMBL592841 0.90
Fluoride SCHEMBL1260469 0.90 TSHR (0.36)
Hydrochloric Acid SCHEMBL8653125 0.90 TSHR (0.36)
Fluoride SCHEMBL1260466 0.90
SCHEMBL11772865 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11346008-B2 Ruthenium etching composition and method ENTEGRIS, INC. (US) 2022-05-31 US claimed
CN-113845838-A Amphiphilic siloxane gel and preparation method thereof 盖科(浙江)生物科技有限公司 2021-12-28 CN claimed
EP-3894512-A1 RUTHENIUM ETCHING COMPOSITION AND METHOD Entegris, Inc. (US) 2021-10-20 EP claimed
CN-113307826-A Preparation method of 9-phosphoryl fluorene compound 西北民族大学 2021-08-27 CN claimed
CN-113195681-A Ruthenium etching composition and method 恩特格里斯公司 2021-07-30 CN claimed
WO-2020123126-A1 RUTHENIUM ETCHING COMPOSITION AND METHOD ENTEGRIS, INC. (US) 2020-06-18 WO claimed
US-20200190673-A1 RUTHENIUM ETCHING COMPOSITION AND METHOD MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT 2020-06-18 US claimed
CN-107177040-B A kind of cellulose solution and its dissolving method and application 武汉大学 2019-10-25 CN claimed
CN-106622356-B A kind of copper modified molecular screen selective reduction catalyst and its preparation method and application 中触媒新材料股份有限公司 2019-03-05 CN claimed
CN-107735455-A Fast setting coating compositions having low pH stability and water resistance 阿科玛股份有限公司 2018-02-23 CN claimed
US-20050222411-A1 Method for the production of monohydro-perfluoroalkanes, bis (perfluoroalkyl) phosphinates and perfluoroalkylphosphonates MERCK PATENT GMBH (DE) 2005-10-06 US claimed
US-20040225055-A1 protective coating on substrate ; film accumulates impurities; removal by applying solution at alkaline pH; neutralizing polymer PERMATEX, INC. 2004-11-11 US claimed
US-20040122266-A1 Method for producing substituted fluorene monomers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-24 US claimed
US-6562433-B1 Method for the preparation of polycarbonate with reduced levels of fries GENERAL ELECTRIC COMPANY 2003-05-13 US claimed
EP-0901621-A4 DEVICE FOR COLORIMETRIC DETECTION OF EXPLOSIVES AND NARCOTICS LEVY ISRAEL (IL) 1999-11-24 EP claimed
EP-0901621-A1 DEVICE FOR COLORIMETRIC DETECTION OF EXPLOSIVES AND NARCOTICS Levy, Israel (IL) 1999-03-17 EP claimed
WO-1997037212-A1 DEVICE FOR COLORIMETRIC DETECTION OF EXPLOSIVES AND NARCOTICS FRIEDMAN, MARK, M. (IL) 1997-10-09 WO claimed
US-5648047-A Device for colorimetric detection of explosives and narcotics ISRAEL LEVY (IL) 1997-07-15 US claimed
US-5354719-A Forming mixture of non-alkali metal, templating agent and organic base, adding silicon additive to form metallosilicate hydrogel, aging, washing, drying and heating INTEVEP, S.A. (VE) 1994-10-11 US claimed
US-5130399-A Using a basic catalysi and a dehydrating agent for producing polysiloxanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-14 US claimed