SCHEMBL6759698

SCHEMBL6759698

CCCCOc1cn(C(C)c2ccccc2)c(=O)o1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MET P08581 4/20 0.39
FAAH O00519 1/20 0.39
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TP53 P04637 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
GAA P10253 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GPR88 Q9GZN0 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6759730 0.93 MET (0.40) METFAAHLMNASMN1; SMN2TP53
SCHEMBL6757207 0.88 PLA2G4A (0.40) LMNASMN1; SMN2TP53MEN1KMT2A
SCHEMBL6757236 0.88 FAAH (0.42) METFAAHLMNAMEN1KMT2A
SCHEMBL6762431 0.83 MET (0.43) METFAAHLMNAMEN1KMT2A
SCHEMBL4679478 0.80 FAAH (0.51) METFAAHMEN1KMT2AALDH1A1
SCHEMBL4676274 0.80 FAAH (0.51) METFAAHMEN1KMT2AALDH1A1
SCHEMBL4678103 0.79 FAAH (0.43) METFAAHMEN1KMT2AALDH1A1
SCHEMBL4678109 0.79 FAAH (0.43) METFAAHMEN1KMT2AALDH1A1
SCHEMBL4680402 0.78 FAAH (0.46) METFAAHMEN1KMT2AALDH1A1
SCHEMBL6764349 0.78 FAAH (0.46) METFAAHMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 MET 2422/4885FAAH 183/4885LMNA 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.