SCHEMBL6757207

SCHEMBL6757207

CCCCOc1cn(C(c2ccccc2)c2ccccc2)c(=O)o1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 2/20 0.40
ALDH1A1 P00352 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 2/20 0.37
GAA P10253 2/20 0.37
LTA4H P09960 2/20 0.36
LMNA P02545 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP19A1 P11511 3/20 0.36
PTPN1 P18031 1/20 0.35
NPY1R P25929 1/20 0.34
NPY2R P49146 1/20 0.34
GPR88 Q9GZN0 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6759586 0.93 GAA (0.38) PLA2G4AALDH1A1TSHRTP53GAA
SCHEMBL6759698 0.88 MET (0.39) ALDH1A1L3MBTL1TSHRTP53GAA
SCHEMBL6761258 0.87 GAA (0.39) L3MBTL1TSHRGAAMEN1KMT2A
SCHEMBL6759730 0.81 MET (0.40) ALDH1A1TSHRTP53LMNAMEN1
SCHEMBL6760443 0.81 GAA (0.41) GAALMNAMEN1KMT2A
SCHEMBL4681001 0.80 FAAH (0.42) PLA2G4AGAACYP19A1
SCHEMBL6759635 0.77 GAA (0.40) TSHRTP53GAALMNAMEN1
SCHEMBL6760099 0.76 GAA (0.41) TSHRGAALTA4HCYP19A1
SCHEMBL6757236 0.75 FAAH (0.42) LMNAMEN1KMT2A
SCHEMBL6764255 0.74 TP53 (0.45) ALDH1A1L3MBTL1TSHRTP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 PLA2G4A 1234/4885ALDH1A1 11/4885L3MBTL1 1543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.