Isosakutanetin

Isosakutanetin

SCHEMBL676015

COc1ccc([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 1.00
CYP1A2 P05177 6/20 1.00
CYP1B1 Q16678 6/20 1.00
CYP19A1 P11511 7/20 0.80
MAPT P10636 4/20 0.80
ALDH1A1 P00352 3/20 0.80
TDP1 Q9NUW8 2/20 0.80
ATM Q13315 2/20 0.80
ADORA3 P0DMS8 1/20 0.80
TAS2R31 P59538 1/20 0.80
CYP3A4 P08684 6/20 0.76
CYP2C19 P33261 4/20 0.76
HSD17B10 Q99714 4/20 0.76
CYP2C9 P11712 3/20 0.76
CA12 O43570 3/20 0.76
CA4 P22748 3/20 0.76
CA7 P43166 3/20 0.76
DPP4 P27487 2/20 0.76
GSK3B P49841 2/20 0.76
MEN1 O00255 2/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isosakutanetin SCHEMBL31128790 1.00 CYP1A1 (1.00) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
Isosakutanetin SCHEMBL5067423 1.00 CYP1A1 (1.00) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
Isosakutanetin SCHEMBL29358328 1.00 CYP1A1 (1.00) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
SCHEMBL16710297 0.94 CYP19A1 (0.90) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
SCHEMBL16710295 0.94 CYP19A1 (0.90) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
Isosakutanetin SCHEMBL2146746 0.90 CYP1A1 (0.82) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
Naringenin SCHEMBL7668757 0.90 CYP1A1 (0.82) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
SCHEMBL13906136 0.89 CYP1A1 (0.80) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
Alpinetin SCHEMBL30741428 0.89 CYP1A1 (0.80) CYP1A1CYP1A2CYP1B1CYP19A1MAPT
Alpinetin SCHEMBL29580312 0.89 CYP1A1 (0.80) CYP1A1CYP1A2CYP1B1CYP19A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1099 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP claimed
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
US-20240398752-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LIVER CIRRHOSIS COMPRISING ISOSAKURANETIN OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2024-12-05 US claimed
CN-118697017-A Sweetness and taste improvement of steviol glycoside or mogroside sweetener with flavonoids 可口可乐公司 2024-09-27 CN claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2024156879-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO claimed
WO-2024156359-A1 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO claimed
US-11980184-B2 Method of making a flavonoid solution and applications thereof for plant growth promotion, seed coating, pathogen elimination, and herbicide stunting effect removal THE BIO CONSULTING (PTY) LTD (ZA) 2024-05-14 US claimed
US-20040081734-A1 Method for selectively obtaining antioxidant rich extracts from citrus fruits QUEEN BIOACTIVES PTY LTD (AU) 2004-04-29 US claimed
US-20040057908-A1 Oral compositions and use thereof NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2004-03-25 US claimed
EP-1399119-A2 ORAL COMPOSITIONS AND USE THEREOF University of Rochester (US) 2004-03-24 EP claimed
US-6528099-B1 Extracts from the cells, frit, core, and peels of citrus fruits, comprises a) employing water treatment and solids extraction of the citrus fruit; b) employing separation technology and/or membrane technology on the extracts, ADUMIM CHEMICALS LTD. (IL) 2003-03-04 US claimed
WO-2002047615-A2 ORAL COMPOSITIONS AND USE THEREOF UNIVERSITY OF ROCHESTER (US) 2002-06-20 WO claimed
EP-1143810-A1 A METHOD FOR SELECTIVELY OBTAINING ANTIOXIDANT RICH EXTRACTS FROM CITRUS FRUITS ADUMIM CHEMICALS LTD. (IL) 2001-10-17 EP claimed
US-6183731-B1 APPLYING COSMETIC WITH BACTERIAL 4-ENE REDUCTASE AND/OR 5A-REDUCTASE INHIBITOR UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. 2001-02-06 US claimed
WO-2000032062-A1 A METHOD FOR SELECTIVELY OBTAINING ANTIOXIDANT RICH EXTRACTS FROM CITRUS FRUITS ADUMIM CHEMICALS LTD. (IL) 2000-06-08 WO claimed
WO-2000001355-A1 METHOD OF REDUCING OR PREVENTING MALODOUR UNILEVER PLC (GB) 2000-01-13 WO claimed
US-4105675-A REDUCING ACYLATED FLAVANONE WITH ALKALI BOROHYDRIDE TO REMOVE OXYGEN FUNCTION AT 4-POSITION; OXIDIZING WITH HALOGENATED BENZOQUINONE TO FORM SALT THE COCA-COLA COMPANY (US) 1978-08-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240398752-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LIVER CIRRHOSIS COMPRISING ISOSAKURANETIN OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT ALPL, GOT1, GYS2 CYP1A1 3324/4885CYP1A2 1355/4885CYP1B1 2838/4885
US-20040057908-A1 Oral compositions and use thereof UGGT1, DPM1, B4GALT1 CYP1A1 578/4885CYP1A2 355/4885CYP1B1 992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.