Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018378 | 0.91 | MAPT (0.34) | CYP19A1CYP11B2TDP1ESR1MMP9 | |
| SCHEMBL2510220 | 0.90 | CYP19A1 (0.42) | CYP19A1CYP11B2TDP1ESR1PTGS2 | |
| SCHEMBL2499606 | 0.89 | RAB9A (0.38) | CYP19A1CYP11B2TDP1ESR1MMP9 | |
| SCHEMBL2499605 | 0.89 | RAB9A (0.38) | CYP19A1CYP11B2TDP1ESR1MMP9 | |
| SCHEMBL19832033 | 0.88 | ALDH1A1 (0.43) | ESR1MMP9HDAC8HDAC6CYP1A2 | |
| SCHEMBL14018430 | 0.87 | L3MBTL1 (0.33) | CYP19A1CYP11B2TDP1ESR1MMP9 | |
| SCHEMBL28304106 | 0.81 | CYP19A1 (0.41) | CYP19A1CYP11B2TDP1ESR1MMP9 | |
| SCHEMBL2508288 | 0.77 | CES2 (0.40) | TDP1PTGS2MEN1MAPTKMT2A | |
| SCHEMBL2508290 | 0.77 | CES2 (0.40) | TDP1PTGS2MEN1MAPTKMT2A | |
| SCHEMBL2509405 | 0.76 | PTGS2 (0.42) | TDP1ESR1PTGS2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703146-B1 | ELECTRON INJECTION OR ELECTRON TRANSPORTING LAYER HAS AN IONIZATION POTENTIAL HIGHER THAN THAT OF THE LUMINESCENT LAYER | NEC CORPORATION (JP) | 2004-03-09 | — | — | US | disclosed |