Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763514 | 1.00 | OPRM1 (0.31) | OPRM1TRPA1TRPM8 | |
| Iodide SCHEMBL6763889 | 0.71 | CCR1 (0.38) | OPRM1TRPM8 | |
| Iodide SCHEMBL6763887 | 0.71 | LMNA (0.38) | OPRM1TRPM8 | |
| SCHEMBL4668738 | 0.65 | CHRM2 (0.45) | OPRM1 | |
| SCHEMBL6764769 | 0.62 | — | — | |
| SCHEMBL5244036 | 0.62 | NPSR1 (0.43) | OPRM1 | |
| SCHEMBL12484267 | 0.62 | NPSR1 (0.43) | OPRM1 | |
| SCHEMBL5824340 | 0.61 | ESR2 (0.49) | OPRM1TRPA1TRPM8 | |
| SCHEMBL28928311 | 0.60 | TRPM8 (0.39) | OPRM1TRPA1TRPM8 | |
| SCHEMBL6764772 | 0.60 | PDE10A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730788-B1 | COUPLING WITH KETONE IN PRESENCE OF LANTHANIDE II METAL COMPOUND | UNIVERSITY OF NOTRE DAME | 2004-05-04 | — | — | US | disclosed |