Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 3/20 | 0.32 |
| ▸ | ADH1A | P07327 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 2/20 | 0.30 |
| ▸ | ADH7 | P40394 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403213 | 1.00 | CTRB1 (0.33) | CTRB1ADH1BADH1AALDH1A1TSHR | |
| SCHEMBL10816103 | 0.81 | CTRB1 (0.35) | CTRB1 | |
| SCHEMBL17074053 | 0.79 | ADH1B (0.34) | CTRB1ADH1BADH1ATSHRADH1C | |
| SCHEMBL11126612 | 0.74 | CTRB1 (0.31) | CTRB1 | |
| SCHEMBL16142754 | 0.73 | — | — | |
| SCHEMBL9060305 | 0.73 | — | — | |
| SCHEMBL14867596 | 0.73 | — | — | |
| SCHEMBL11795515 | 0.69 | ALOX15 (0.36) | — | |
| SCHEMBL7191306 | 0.68 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL8634789 | 0.68 | CTRB1 (0.35) | CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114106090-B | Production process of aspartame | 江苏汉光生物工程有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114106090-A | Production process of aspartame | 江苏汉光生物工程有限公司 | 2022-03-01 | — | — | CN | disclosed |
| US-8431612-B2 | Ester prodrugs of prostratin and related phorbol compounds | SALVIA SCIENCES, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431612-B2 | Ester prodrugs of prostratin and related phorbol compounds | SALVIA SCIENCES, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20090163587-A1 | ESTER PRODRUGS OF PROSTRATIN AND RELATED PHORBOL COMPOUNDS | SALVIA SCIENCES, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090163587-A1 | ESTER PRODRUGS OF PROSTRATIN AND RELATED PHORBOL COMPOUNDS | SALVIA SCIENCES, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| US-6730289-B2 | HAIR STYLING MIXTURE COMPRISING AN ACYLATED CARBAMATE GROUP MODIFIED POLYURETHANE AND ACCEPTABLE CARRIER OR DILUENT; NO DEPOSITS ON HAIR, WATER SOLUBLE | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-05-04 | — | — | US | disclosed |
| US-20020176837-A1 | Cosmetic composition | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2002-11-28 | — | — | US | disclosed |
| US-6437145-B1 | REACTING N-PROTECTED AMINODICARBOXYLIC ACIDS WITH A DEHYDRATING AGENT TO FORM CYCLIC ANHYDRIDES WHICH ARE REACTED WITH CARBONYL COMPOUNDS; FOR THE ALPHA-SELECTIVE PRODUCTION OF ESTERS OR AMIDES OF DICARBOXYLIC AMINO ACIDS | DEGUSSA-HULS AG (DE) | 2002-08-20 | — | — | US | disclosed |
| WO-2002058645-A1 | POLYURETHANES, COSMETIC COMPOSITIONS CONTAINING THEM AND METHOD OF PREPARATION | UNILEVER PLC (GB) | 2002-08-01 | — | — | WO | disclosed |
| US-6051715-A | Method of producing oxazolidinones, the use thereof and novel oxazolidinones | DEGUSSA-HULS AG (DE) | 2000-04-18 | — | — | US | disclosed |
| EP-0468063-B1 | A one-pot process for the preparation of alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride | NUTRASWEET CO (US) | 1996-06-05 | — | — | EP | disclosed |
| EP-0466959-B1 | Process for the preparation of n-formyl-l-aspartic anhydride | NUTRASWEET CO (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5476961-A | Formylating L-aspartic acid, coupling with L-phenylalanine in the presence of acetic acid, deformylating, removing acid residues, esterifying, forming salt | THE NUTRASWEET COMPANY (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0468063-A1 | A one-pot process for the preparation of alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride | THE NUTRASWEET COMPANY (US) | 1992-01-29 | — | — | EP | disclosed |
| WO-1992000953-A1 | A ONE-POT PROCESS FOR THE PREPARATION OF ALPHA-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER HYDROCHLORIDE | THE NUTRASWEET COMPANY (US) | 1992-01-23 | — | — | WO | disclosed |
| EP-0466959-A1 | Process for the preparation of n-formyl-l-aspartic anhydride | THE NUTRASWEET COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5053532-A | Agitating N-formyl-L-aspartic anhydride with L-phenylalanine in presence of acid, alcohol, alkyl ester | THE NUTRA SWEET COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| US-4760164-A | Coupling formyl-L-aspartic anhydride with L-phenylalanine esterification, netralization and filtration | KOREA GREEN CROSS CORPORATION (KR) | 1988-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163587-A1 | ESTER PRODRUGS OF PROSTRATIN AND RELATED PHORBOL COMPOUNDS | PMAIP1, PTGIR, PTGDR | CTRB1 2632/4885ADH1B 2298/4885ADH1A 1643/4885 |
| US-20020176837-A1 | Cosmetic composition | POLR1C, ALKBH5, HAT1 | CTRB1 2640/4885ADH1B 3167/4885ADH1A 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.