Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.64 |
| ▸ | MMP13 | P45452 | 16/20 | 0.60 |
| ▸ | MMP2 | P08253 | 8/20 | 0.56 |
| ▸ | MMP9 | P14780 | 5/20 | 0.56 |
| ▸ | MMP3 | P08254 | 4/20 | 0.56 |
| ▸ | MMP14 | P50281 | 3/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
| ▸ | MMP16 | P51512 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764872 | 0.86 | MMP13 (0.70) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL6764875 | 0.86 | MMP13 (0.70) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL6764610 | 0.86 | MMP13 (0.70) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7360559 | 0.86 | MMP13 (0.62) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7924711 | 0.79 | MMP2 (0.63) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7922815 | 0.78 | MMP1 (0.59) | MMP1MMP13MMP2MMP9MMP3 | |
| Hydrochloric Acid SCHEMBL7689947 | 0.78 | ADAM33 (0.54) | MMP1MMP13MMP2MMP9MMP3 | |
| Hydrochloric Acid SCHEMBL7301531 | 0.76 | MMP13 (0.67) | MMP1MMP13MMP2MMP9MMP3 | |
| Hydrochloric Acid SCHEMBL7301537 | 0.76 | MMP13 (0.67) | MMP1MMP13MMP2MMP9MMP3 | |
| SCHEMBL7690202 | 0.76 | MMP13 (0.65) | MMP1MMP13MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476027-B1 | N-hydroxy 4-sulfonyl butanamide compounds | MONSANTO COMPANY | 2002-11-05 | — | — | US | disclosed |