Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028602 | 0.88 | OPRK1 (0.57) | CNR1MEN1KMT2AMAPTHTT | |
| SCHEMBL6767270 | 0.80 | KMT2A (0.59) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL5629271 | 0.80 | LMNA (0.55) | CNR1MEN1KMT2AADRB1ADRB3 | |
| SCHEMBL6773829 | 0.79 | CNR1 (0.55) | CNR1MEN1KMT2AMAPTHTT | |
| SCHEMBL2568962 | 0.77 | HTT (0.52) | CNR1MEN1KMT2AMAPTHTT | |
| SCHEMBL15995630 | 0.73 | ADRB2 (0.69) | SMN1; SMN2ADRB1ADRB3ADRB2 | |
| SCHEMBL5436525 | 0.71 | KMT2A (0.63) | CNR1MEN1KMT2AALDH1A1TAAR1 | |
| SCHEMBL6318456 | 0.70 | TDP1 (0.58) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL22834267 | 0.70 | CNR1 (1.00) | CNR1MEN1KMT2AMAPTHTT | |
| SCHEMBL29615227 | 0.70 | CNR1 (1.00) | CNR1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703405-B2 | RESPIRATORY SYSTEM AND SLEEP DISORDERS; HPOTENSIVE AGENTS; ANTIISCHEMIC, ANTISTROKE, ANTIEDEMA, ANTISTROKE, ANTICARCINOGENIC, AND ANTIDIABETIC AGENTS; ATHEROSCLEROSIS, GALLSTONE TREATMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-03-09 | — | — | US | disclosed |
| US-20030171580-A1 | Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171580-A1 | Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them | ABCB11, SLC10A1, REN | CNR1 563/4885MEN1 2747/4885KMT2A 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.