Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584608 | 0.85 | FAAH (0.60) | FAAHALDH1A1DRD4CYP2D6GRIN2B | |
| SCHEMBL1331198 | 0.81 | FAAH (0.65) | FAAHDRD4HTR1AHTR7MEN1 | |
| SCHEMBL17289123 | 0.81 | FAAH (0.65) | FAAHDRD4HTR1AHTR7MEN1 | |
| SCHEMBL6583064 | 0.80 | FAAH (0.50) | FAAHDRD4GRIN2BHTR1AHTR7 | |
| SCHEMBL27140396 | 0.79 | FAAH (0.57) | FAAHALDH1A1DRD4CYP2D6GRIN2B | |
| SCHEMBL13940592 | 0.79 | HRH3 (0.58) | FAAHDRD4GRIN2BHTR1AHTR7 | |
| SCHEMBL23750987 | 0.77 | FAAH (0.55) | FAAHDRD4HTR1AHTR7MEN1 | |
| SCHEMBL7495658 | 0.77 | FAAH (0.55) | FAAHDRD4HTR1AHTR7MEN1 | |
| SCHEMBL13150416 | 0.77 | FAAH (0.53) | FAAHALDH1A1DRD4CYP2D6HTR1A | |
| SCHEMBL6770148 | 0.77 | CCR2 (0.81) | CCR2ALDH1A1CYP2D6KCNA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-0914319-B1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LTD (JP) | 2001-11-21 | — | — | EP | disclosed |