Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769373 | 0.81 | MTNR1B (0.47) | ALDH1A1THRATHRBMTNR1AMTNR1B | |
| SCHEMBL6769171 | 0.81 | THRB (0.31) | THRB | |
| SCHEMBL6775933 | 0.74 | MTNR1B (0.46) | KDM4ETHRATHRBMTNR1BLMNA | |
| SCHEMBL6775732 | 0.72 | RORC (0.54) | ALDH1A1THRATHRBMTNR1AMTNR1B | |
| SCHEMBL6765992 | 0.71 | AR (0.52) | RAB9ATHRATHRB | |
| SCHEMBL6775887 | 0.69 | THRB (0.36) | KDM4EALDH1A1RAB9ATHRBLMNA | |
| SCHEMBL15434478 | 0.68 | KDM4E (0.42) | KDM4EALDH1A1TP53RAB9AHSD17B10 | |
| SCHEMBL3222511 | 0.66 | THRB (0.47) | THRATHRB | |
| SCHEMBL3227804 | 0.65 | THRB (0.39) | ALDH1A1THRATHRB | |
| SCHEMBL3227821 | 0.64 | THRB (0.41) | ALDH1A1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723717-B1 | CARDIAC-SPARING; SIDE EFFECT REDUCTION | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2004-04-20 | — | — | US | disclosed |