Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775933 | 0.85 | MTNR1B (0.46) | ARMEN1KMT2ATHRATHRB | |
| SCHEMBL7584863 | 0.84 | THRB (0.57) | ARMEN1KMT2ARAB9AATM | |
| SCHEMBL6769373 | 0.82 | MTNR1B (0.47) | THRATHRB | |
| SCHEMBL22959249 | 0.73 | RORC (0.73) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL28922759 | 0.72 | RAB9A (0.66) | ARMEN1KMT2ARAB9AATM | |
| SCHEMBL6775732 | 0.71 | RORC (0.54) | MEN1KMT2ATHRATHRB | |
| SCHEMBL6775887 | 0.70 | THRB (0.36) | MEN1KMT2ARAB9ANPC1MCHR1 | |
| SCHEMBL7097286 | 0.70 | THRB (0.75) | THRATHRB | |
| SCHEMBL30958899 | 0.69 | ATM (0.89) | MEN1KMT2ARAB9AATMNPC1 | |
| SCHEMBL16343752 | 0.69 | PGR (0.57) | ARMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723717-B1 | CARDIAC-SPARING; SIDE EFFECT REDUCTION | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2004-04-20 | — | — | US | disclosed |