Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 20/20 | 0.60 |
| ▸ | F13A1 | P00488 | 2/20 | 0.53 |
| ▸ | TGM1 | P22735 | 2/20 | 0.53 |
| ▸ | TGM6 | O95932 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763781 | 0.87 | SIRT2 (0.56) | TGM2 | |
| SCHEMBL6766563 | 0.81 | ITGB3 (0.65) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL13598866 | 0.81 | ITGB3 (0.65) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL6445875 | 0.81 | TGM2 (0.58) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL5712251 | 0.80 | ITGB3 (0.70) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL7294359 | 0.79 | DPP4 (0.58) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL17007552 | 0.78 | TGM2 (0.83) | TGM2F13A1TGM1TGM6 | |
| Hydrochloric Acid SCHEMBL6767096 | 0.78 | DPP4 (0.58) | TGM2F13A1TGM1TGM6 | |
| SCHEMBL30054191 | 0.77 | CTSL (0.56) | TGM2F13A1TGM1 | |
| SCHEMBL6763753 | 0.77 | F2 (0.35) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716843-B2 | INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV | LES LABORATOIRES SERVIER (FR) | 2004-04-06 | — | — | US | disclosed |
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | LES LABORATOIRES SERVIER (FR) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087950-A1 | New alpha-amino acid sulphonyl compounds | DNPEP, DPP4, DPP7 | TGM2 550/4885F13A1 1939/4885TGM1 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.