SCHEMBL677125

SCHEMBL677125

CCCCCCCC/C=C/CCCCCCCC1=NC(C)(CO)CO1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.38
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36
CDC25C P30307 1/20 0.36
PRKCA P17252 9/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677126 1.00 EPHX2 (0.38) EPHX2CDC25ACDC25BCDC25CPRKCA
SCHEMBL5986963 1.00 EPHX2 (0.38) EPHX2CDC25ACDC25BCDC25CPRKCA
SCHEMBL5986968 1.00 EPHX2 (0.38) EPHX2CDC25ACDC25BCDC25CPRKCA
SCHEMBL9787920 0.91 PRKCA (0.34) PRKCA
SCHEMBL10618565 0.91 PRKCA (0.34) PRKCA
SCHEMBL10619653 0.91 PRKCA (0.34) PRKCA
SCHEMBL10491918 0.91 PRKCA (0.34) PRKCA
SCHEMBL9787876 0.91 PRKCA (0.34) PRKCA
SCHEMBL676589 0.91 PRKCA (0.34) PRKCA
SCHEMBL11210120 0.89 PRKCA (0.36) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220249446-A1 Composition Comprising at Least One Oxazoline for Inhibiting the Growth of Malassezia Yeasts Involved in Cradle Cap, in Particular LABORATOIRES EXPANSCIENCE (FR) 2022-08-11 US claimed
EP-3996674-A1 COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE FOR INHIBITING THE GROWTH OF MALASSEZIA YEASTS INVOLVED IN CRADLE CAP, IN PARTICULAR Laboratoires Expanscience (FR) 2022-05-18 EP claimed
EP-2953611-B1 USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS EXPANSCIENCE LAB (FR) 2021-08-18 EP claimed
WO-2021009142-A1 COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE FOR INHIBITING THE GROWTH OF MALASSEZIA YEASTS INVOLVED IN CRADLE CAP, IN PARTICULAR LABORATOIRES EXPANSCIENCE (FR) 2021-01-21 WO claimed
US-20200085897-A1 Extract of Aerial Parts of Maca Rich in Polyphenols and Composition Comprising Same LABORATOIRES EXPANSCIENCE (FR) 2020-03-19 US claimed
EP-2654765-B1 EXTRACT OF THE AERIAL PARTS OF MACA RICH IN POLYPHENOL AND COMPOSITION COMPRISING THE EXTRACT EXPANSCIENCE LAB (FR) 2019-03-13 EP claimed
EP-2654766-B1 EXTRACT OF THE PULP AND/OR PEEL OF AVOCADO RICH IN POLYPHENOLS AND COSMETIC, DERMATOLOGIC OR NUTRACEUTIC COMPOSITIONS COMPRISING THEREOF EXPANSCIENCE LAB (FR) 2018-10-10 EP claimed
EP-2654762-B1 EXTRACT OF THE AERIAL PARTS OF GYNANDROPSIS GYNANDRA AND COSMETIC, DERMATOLIGIC AND PHARMACEUTIC COMPOSITIONS COMPRISING THE EXTRACT EXPANSCIENCE LAB (FR) 2018-09-26 EP claimed
US-20150374605-A1 USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS LABORATOIRES EXPANSCIENCE (FR) 2015-12-31 US claimed
EP-2953611-A1 USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS Laboratoires Expanscience (FR) 2015-12-16 EP claimed
US-20090274637-A1 Depigmenting or Brigthening Cosmetic Composition at Least One Oxazolin as an Active Ingredient LABORATOIRES EXPANSCIENCE (FR) 2009-11-05 US claimed
EP-1874410-B1 DEPIGMENTING OR BRIGHTENING COSMETIC COMPOSITION COMPRISING AT LEAST ONE OXAZOLIN AS AN ACTIVE INGREDIENT EXPANSCIENCE LAB (FR) 2009-03-11 EP claimed
EP-1874410-A1 DEPIGMENTING OR BRIGHTENING COSMETIC COMPOSITION COMPRISING AT LEAST ONE OXAZOLIN AS AN ACTIVE INGREDIENT Laboratoires Expanscience (FR) 2008-01-09 EP claimed
EP-1648569-B1 COSMETIC USE OF A COMPOSITION CONTAINING AT LEAST ONE OXAZOLINE, SERVING AS AN ACTIVE SUBSTANCE, AS A SLIMMING PRODUCT AND/OR FOR PREVENTING AND/OR TREATING CELLULITE EXPANSCIENCE LAB (FR) 2006-12-06 EP claimed
WO-2006114443-A1 DEPIGMENTING OR BRIGHTENING COSMETIC COMPOSITION COMPRISING AT LEAST ONE OXAZOLIN AS AN ACTIVE INGREDIENT LABORATOIRES EXPANSCIENCE (FR) 2006-11-02 WO claimed
US-20060122246-A1 Cosmetic use of a composition containing at least one oxazoline, serving as an active substance, as a slimming product and/or for preventing and/or treating cellulite LABORATOIRES EXPANSCIENCE 2006-06-08 US claimed
EP-1648569-A1 COSMETIC USE OF A COMPOSITION CONTAINING AT LEAST ONE OXAZOLINE, SERVING AS AN ACTIVE SUBSTANCE, AS A SLIMMING PRODUCT AND/OR FOR PREVENTING AND/OR TREATING CELLULITE Laboratoires Expanscience (FR) 2006-04-26 EP claimed
WO-2004112741-A1 COSMETIC USE OF A COMPOSITION CONTAINING AT LEAST ONE OXAZOLINE, SERVING AS AN ACTIVE SUBSTANCE, AS A SLIMMING PRODUCT AND/OR FOR PREVENTING AND/OR TREATING CELLULITE LABORATOIRES EXPANSCIENCE (FR) 2004-12-29 WO claimed
EP-1458349-A1 COMPOSITION COMPRISING AT LEAST AN OXAZOLIN FOR INHIBITING LANGERHANS CELL MIGRATION, AND USES THEREOF Laboratoires Expanscience (FR) 2004-09-22 EP claimed
WO-2003055463-A1 COMPOSITION COMPRISING AT LEAST AN OXAZOLIN FOR INHIBITING LANGERHANS CELL MIGRATION, AND USES THEREOF LABORATOIRES EXPANSCIENCE (FR) 2003-07-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274637-A1 Depigmenting or Brigthening Cosmetic Composition at Least One Oxazolin as an Active Ingredient BRD7, BRD1, TYR EPHX2 1921/4885CDC25A 336/4885CDC25B 571/4885
US-20220249446-A1 Composition Comprising at Least One Oxazoline for Inhibiting the Growth of Malassezia Yeasts Involved in Cradle Cap, in Particular OCIAD1, ERG28, CYP51A1 EPHX2 2413/4885CDC25A 380/4885CDC25B 635/4885
US-20150374605-A1 USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS HES1, PRUNE1, DSG1 EPHX2 1241/4885CDC25A 314/4885CDC25B 954/4885
US-20060122246-A1 Cosmetic use of a composition containing at least one oxazoline, serving as an active substance, as a slimming product and/or for preventing and/or treating cellulite CUTA, SYMPK, LPXN EPHX2 2157/4885CDC25A 1450/4885CDC25B 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.