Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 5/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769930 | 0.93 | LMNA (0.47) | LMNATHRBKDRMAPTALDH1A1 | |
| SCHEMBL7077388 | 0.86 | ALDH1A1 (0.48) | LMNAKDRALDH1A1METTL3HTT | |
| SCHEMBL6769860 | 0.84 | SYK (0.52) | LMNAKDRMAPTSYKHTT | |
| SCHEMBL6608523 | 0.83 | SYK (0.48) | LMNAKDRMAPTSYKHTT | |
| SCHEMBL6770161 | 0.81 | SYK (0.47) | LMNAKDRMAPTALDH1A1SYK | |
| SCHEMBL6777397 | 0.81 | SYK (0.46) | LMNAKDRMAPTSYKHTT | |
| SCHEMBL6766170 | 0.81 | KDR (0.46) | KDRALDH1A1SYKHTTCDK2 | |
| SCHEMBL761284 | 0.80 | SYK (0.54) | KDRSYKHTTCDK2DYRK1A | |
| SCHEMBL7081412 | 0.79 | ALDH1A1 (0.48) | LMNAKDRALDH1A1METTL3HTT | |
| SCHEMBL6772485 | 0.79 | HSD17B10 (0.46) | LMNATHRBALDH1A1FLT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762189-B1 | HEPATITIS B VIRUS AND HUMAN IMMUNODEFICIENCY VIRUS ANTIPROLIFERATION AGENTS; REDUCED CHANCE OF TOXICITY, SIDE EFFECTS, AND DEVELOPMENT OF RESISTANT VIRAL STRAINS | DONG WHA PHARM. IND. CO., LTD. (KR) | 2004-07-13 | — | — | US | disclosed |