Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778477 | 0.87 | QPCT (0.44) | LMNAGAAKMT2A | |
| SCHEMBL6774160 | 0.86 | HPGD (0.47) | LMNAGAATMIGD3ADORA2AADORA1 | |
| SCHEMBL6778362 | 0.85 | HRH2 (0.38) | LMNAADORA2AHRH4HRH2MAPK1 | |
| SCHEMBL6778820 | 0.85 | QPCT (0.38) | HRH4ALDH1A1HRH2KMT2ATDP1 | |
| SCHEMBL6773010 | 0.83 | ALDH1A1 (0.43) | GAATMIGD3ADORA2AADORA1ADORA2B | |
| SCHEMBL6768483 | 0.81 | DRD3 (0.44) | LMNAGAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6776668 | 0.80 | SMN1; SMN2 (0.44) | LMNAGAATAAR1SMN1; SMN2RAB9A | |
| SCHEMBL6774520 | 0.80 | TP53 (0.37) | LMNATMIGD3ADORA2AADORA1ADORA2B | |
| SCHEMBL6777509 | 0.80 | FAAH (0.47) | LMNAGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL6779152 | 0.79 | TLR7 (0.40) | LMNATMIGD3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100402528-C | Urea substituted imidazopyridines | 3M INNOVATIVE PROPERTIES CO (US) | 2008-07-16 | — | — | CN | claimed |
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |