Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773010 | 0.85 | ALDH1A1 (0.43) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3864050 | 0.85 | TLR7 (0.46) | HPGDALOX15HSD17B10ALDH1A1TSHR | |
| SCHEMBL6773902 | 0.81 | ALDH1A1 (0.44) | HPGDALOX15HSD17B10ALDH1A1TSHR | |
| SCHEMBL6098139 | 0.80 | DYRK1A (0.37) | ALDH1A1KDM4E | |
| SCHEMBL6775246 | 0.80 | HDAC1 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL6774160 | 0.80 | HPGD (0.47) | HPGDTSHRKDM4EMEN1KMT2A | |
| SCHEMBL6779679 | 0.79 | HPGD (0.46) | HPGDALOX15HSD17B10ALDH1A1TSHR | |
| SCHEMBL6768483 | 0.79 | DRD3 (0.44) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL6779047 | 0.78 | CYP2C9 (0.43) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL6773196 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |