Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773010 | 0.88 | ALDH1A1 (0.43) | MAPTADORA2AADORA1TMIGD3ALDH1A1 | |
| SCHEMBL6774160 | 0.86 | HPGD (0.47) | L3MBTL1ADORA2AADORA1TMIGD3HDAC1 | |
| SCHEMBL6768483 | 0.82 | DRD3 (0.44) | MAPTALDH1A1HDAC1HDAC2TLR7 | |
| SCHEMBL6777509 | 0.81 | FAAH (0.47) | MAPTHTTALDH1A1HDAC1LMNA | |
| SCHEMBL6773831 | 0.80 | TLR7 (0.40) | MAPTHTTADORA2AADORA1CSNK1D | |
| SCHEMBL6778367 | 0.80 | LMNA (0.44) | MAPTHTTADORA2AADORA1TMIGD3 | |
| SCHEMBL6098139 | 0.80 | DYRK1A (0.37) | ALDH1A1ADCY5MAPK1 | |
| SCHEMBL6775246 | 0.79 | HDAC1 (0.41) | L3MBTL1ADORA2AALDH1A1HDAC1HDAC2 | |
| SCHEMBL6778860 | 0.79 | TLR7 (0.44) | CSNK1DTLR7TLR8 | |
| SCHEMBL6779152 | 0.78 | TLR7 (0.40) | ADORA2AADORA1TMIGD3ALDH1A1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |