SCHEMBL677435

SCHEMBL677435

CC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.80

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.80
GSTK1 Q9Y2Q3 1/20 0.80
GLO1 Q04760 2/20 0.56
NOD1 Q9Y239 10/20 0.47
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
PGGT1B P53609 1/20 0.43
FOLH1 Q04609 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.38
PTGS2 P35354 1/20 0.38
THPO P40225 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13160954 1.00 PTGS1 (0.80) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL20298530 0.91 PTGS1 (0.92) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL8215210 0.91 PTGS1 (0.92) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL8215201 0.91 PTGS1 (0.92) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL20298529 0.91 PTGS1 (0.92) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL28212822 0.90 PTGS1 (0.90) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL3790499 0.89 PTGS1 (0.95) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL3790504 0.89 PTGS1 (0.95) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL1105665 0.89 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FNTA
Glutathione SCHEMBL14364095 0.89 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230144527-A1 STABLE ASCORBIC ACID COMPOSITIONS AND METHODS OF USING SAME RENOVION, INC. 2023-05-11 US disclosed
US-9963621-B2 Manufacturing method of quantum dot glue, quantum dot glue and quantum dot polarizer SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-05-08 US disclosed
US-20180100090-A1 MANUFACTURING METHOD OF QUANTUM DOT GLUE, QUANTUM DOT GLUE AND QUANTUM DOT POLARIZER SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-04-12 US disclosed
US-8067380-B2 Glutathione-based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-11-29 US disclosed
US-7704956-B2 Glutathione-based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-04-27 US disclosed
US-7700564-B2 Glutathione based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-04-20 US disclosed
US-20090123531-A1 GLUTATHIONE-BASED DELIVERY SYSTEM INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-05-14 US disclosed
US-20090060991-A1 GLUTATHIONE BASED DELIVERY SYSTEM WANG AE-JUNE 2009-03-05 US disclosed
US-7446096-B2 Glutathione based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2008-11-04 US disclosed
US-20080095836-A1 Glutathione-based delivery system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-04-24 US disclosed
US-20070141133-A1 Liposomes; analgesics; glutathione is covalently bound to polyethylene glycol,wherein the polyethylene glycol is covalently bound to vitamin E or a phospholipid INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070141133-A1 Liposomes; analgesics; glutathione is covalently bound to polyethylene glycol,wherein the polyethylene glycol is covalently bound to vitamin E or a phospholipid GSTO1, GSTP1, GSTA1 PTGS1 17/4885GSTK1 7/4885GLO1 82/4885
US-20080095836-A1 Glutathione-based delivery system GSTP1, GSS, GSTA1 PTGS1 17/4885GSTK1 7/4885GLO1 23/4885
US-20090060991-A1 GLUTATHIONE BASED DELIVERY SYSTEM GPX4, GSTO1, GPX1 PTGS1 30/4885GSTK1 8/4885GLO1 37/4885
US-20090123531-A1 GLUTATHIONE-BASED DELIVERY SYSTEM GSTO1, GPX4, GPX1 PTGS1 29/4885GSTK1 8/4885GLO1 38/4885
US-20230144527-A1 STABLE ASCORBIC ACID COMPOSITIONS AND METHODS OF USING SAME GPX1, GSTA1, GPX4 PTGS1 689/4885GSTK1 11/4885GLO1 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.