Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779541 | 0.89 | TUBB4A (0.45) | ALDH1A1LMNAMAPTHTTNPC1 | |
| SCHEMBL6777299 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL6778932 | 0.83 | ALDH1A1 (0.41) | ALDH1A1POLBLMNAMAPTNPC1 | |
| SCHEMBL6777740 | 0.83 | LMNA (0.46) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL6779180 | 0.82 | KDM4E (0.40) | ALDH1A1POLBHPGDTP53MAPT | |
| SCHEMBL6894485 | 0.81 | MAPT (0.43) | ALDH1A1HPGDTP53LMNAMAPT | |
| SCHEMBL6778341 | 0.81 | TLR7 (0.35) | — | |
| SCHEMBL6773282 | 0.81 | P2RY12 (0.43) | ALDH1A1HPGDKMT2AUSP2CYP1A2 | |
| SCHEMBL6776588 | 0.80 | EPHX2 (0.37) | HTTL3MBTL1 | |
| SCHEMBL6777554 | 0.80 | KDM4E (0.36) | ALDH1A1POLBMAPTHTTSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |