Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777740 | 0.89 | LMNA (0.46) | TLR7HSD17B10CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL6777299 | 0.89 | ALDH1A1 (0.43) | TLR7TLR8SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6779541 | 0.89 | TUBB4A (0.45) | P2RY12MAPK1TSHRALDH1A1KMT2A | |
| SCHEMBL6773545 | 0.89 | TLR7 (0.43) | TLR7TLR8CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL6894485 | 0.88 | MAPT (0.43) | TLR7TLR8HSD17B10CCR2SMN1; SMN2 | |
| SCHEMBL6779180 | 0.83 | KDM4E (0.40) | TLR7TLR8HSD17B10SMN1; SMN2THRB | |
| SCHEMBL6776089 | 0.82 | CCR3 (0.44) | TLR7TLR8SMN1; SMN2CCR3 | |
| SCHEMBL6777443 | 0.81 | ALDH1A1 (0.40) | CYP2D6HSD17B10USP2CYP3A4CYP2C19 | |
| SCHEMBL6778341 | 0.80 | TLR7 (0.35) | TLR7TLR8 | |
| SCHEMBL6783053 | 0.80 | KDM4E (0.44) | TLR7TLR8SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |