Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 5/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774588 | 0.95 | FKBP5 (0.47) | FKBP5FKBP1AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL6783532 | 0.93 | FKBP5 (0.47) | FKBP5FKBP1AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL6779125 | 0.89 | FKBP1A (0.44) | FKBP5FKBP1AKMT2ASMN1; SMN2HTT | |
| SCHEMBL6776757 | 0.86 | FKBP1A (0.47) | FKBP5FKBP1AALDH1A1KMT2A | |
| SCHEMBL6778877 | 0.82 | FKBP5 (0.51) | FKBP5ALDH1A1L3MBTL1TDP1KMT2A | |
| SCHEMBL6784892 | 0.82 | FKBP1A (0.48) | FKBP5FKBP1AALDH1A1 | |
| SCHEMBL6778408 | 0.80 | FKBP5 (0.50) | FKBP5ALDH1A1L3MBTL1TDP1KMT2A | |
| SCHEMBL6776495 | 0.80 | FKBP5 (0.51) | FKBP5FKBP1AKMT2AHTT | |
| SCHEMBL6781032 | 0.77 | FKBP1A (0.47) | FKBP5FKBP1AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6780481 | 0.77 | FKBP5 (0.55) | FKBP5FKBP1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818643-B1 | 3,9-DIAZABICYCLO(3.3.1)NONAN-2-ONE DERIVATIVES; PEPTIDYL-PROLYL ISOMERASE (PPIASE OR ROTAMASE) INHIBITORS; NEUROPROTECTIVE AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2004-11-16 | — | — | US | disclosed |