Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.44 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774588 | 0.94 | FKBP5 (0.47) | FKBP1AFKBP5KMT2AMEN1HTT | |
| SCHEMBL6776757 | 0.93 | FKBP1A (0.47) | FKBP1AFKBP5KMT2A | |
| SCHEMBL6783532 | 0.92 | FKBP5 (0.47) | FKBP1AFKBP5KMT2AMEN1HTT | |
| SCHEMBL6779072 | 0.89 | FKBP5 (0.54) | FKBP1AFKBP5SMN1; SMN2KMT2AHTT | |
| SCHEMBL6781032 | 0.85 | FKBP1A (0.47) | FKBP1AFKBP5LMNASMN1; SMN2KMT2A | |
| SCHEMBL6785090 | 0.81 | FKBP1A (0.50) | FKBP1AFKBP5KMT2AMEN1HTT | |
| SCHEMBL6776495 | 0.79 | FKBP5 (0.51) | FKBP1AFKBP5KMT2AMEN1HTT | |
| SCHEMBL6784892 | 0.79 | FKBP1A (0.48) | FKBP1AFKBP5 | |
| SCHEMBL6785000 | 0.77 | FKBP1A (0.45) | FKBP1AFKBP5LMNAKMT2AMEN1 | |
| SCHEMBL6780481 | 0.76 | FKBP5 (0.55) | FKBP1AFKBP5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818643-B1 | 3,9-DIAZABICYCLO(3.3.1)NONAN-2-ONE DERIVATIVES; PEPTIDYL-PROLYL ISOMERASE (PPIASE OR ROTAMASE) INHIBITORS; NEUROPROTECTIVE AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2004-11-16 | — | — | US | disclosed |