Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773275 | 0.94 | TRPV1 (0.43) | TRPV1EPHX2NR1H4MCHR1HDAC3 | |
| SCHEMBL6773364 | 0.88 | RXFP1 (0.43) | EPHX2MCHR1HDAC3HDAC1TLR7 | |
| SCHEMBL6771355 | 0.88 | POLB (0.47) | TLR7MAPT | |
| SCHEMBL6768729 | 0.87 | TLR7 (0.47) | TLR7MAPT | |
| SCHEMBL6773253 | 0.86 | GAA (0.41) | MAPT | |
| SCHEMBL6774657 | 0.84 | MAPT (0.49) | TLR7MAPT | |
| SCHEMBL6768544 | 0.83 | NPC1 (0.49) | HDAC3HDAC1MAPT | |
| SCHEMBL6772992 | 0.83 | HDAC3 (0.40) | EPHX2MCHR1HDAC3HDAC1TLR7 | |
| SCHEMBL6774530 | 0.83 | TRPV1 (0.42) | TRPV1EPHX2MCHR1HDAC3HDAC1 | |
| SCHEMBL6779678 | 0.82 | NPY5R (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |