Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | PNLIP | P16233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15384455 | 0.80 | ALDH1A1 (0.58) | SCN9AALDH1A1GAAMAPTPTGES | |
| SCHEMBL14754324 | 0.77 | RAB9A (0.47) | SCN9AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL28273947 | 0.75 | RAB9A (0.45) | SCN9AALDH1A1GAANPC1RAB9A | |
| SCHEMBL1386893 | 0.75 | SCN4A (0.42) | SCN9ASCN4AHSPB1ALDH1A1GAA | |
| SCHEMBL6774958 | 0.74 | SCN4A (0.43) | SCN9ASCN4AHSPB1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL3366879 | 0.74 | SCN4A (0.41) | SCN9ASCN4AHSPB1ALDH1A1GAA | |
| SCHEMBL6514066 | 0.72 | ALPL (0.43) | SCN9AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL27560773 | 0.72 | PTGES (0.46) | SCN9ASCN4AALDH1A1MAPTPTGES | |
| SCHEMBL14320585 | 0.71 | CHEK2 (0.42) | SCN9AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL14754382 | 0.71 | KMO (0.47) | SCN9AMEN1KMT2AMETMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737418-B2 | CENTRAL NERVOUS SYSTEM DISORDERS; ANTICONVULSANTS | EURO-CELTIQUE S.A. (LU) | 2004-05-18 | — | — | US | disclosed |
| US-6414011-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | EURO-CELTIQUE S.A. (LU) | 2002-07-02 | — | — | US | disclosed |