Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130886 | 0.86 | TDP1 (0.51) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL678129 | 0.81 | TDP1 (0.47) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorpyrifos-Methyl SCHEMBL21647865 | 0.78 | TDP1 (1.00) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorpyrifos-Methyl SCHEMBL27546 | 0.78 | TDP1 (1.00) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorpyrifos SCHEMBL7908295 | 0.74 | ALDH1A1 (1.00) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorpyrifos SCHEMBL21680 | 0.74 | ALDH1A1 (1.00) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL634976 | 0.74 | TDP1 (0.64) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorpyrifos SCHEMBL28945660 | 0.73 | ALDH1A1 (0.97) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorpyrifos SCHEMBL29011072 | 0.73 | ALDH1A1 (0.97) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorpyrifos SCHEMBL18228939 | 0.73 | ALDH1A1 (0.97) | TDP1MEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160044921-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2016-02-18 | — | — | US | disclosed |
| US-8865683-B2 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AG (DE) | 2014-10-21 | — | — | US | disclosed |
| US-8846567-B2 | Active compound combinations having insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2014-09-30 | — | — | US | disclosed |
| US-20140287915-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2014-09-25 | — | — | US | disclosed |
| US-20120021901-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20110124588-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20100311677-A1 | Active Ingredient Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AG (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20100249070-A1 | Active Compound Combinations Having Insecticidal Properties | BAYER CROPSCIENCE AG (DE) | 2010-09-30 | — | — | US | disclosed |
| US-20090318386-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | FISCHER REINER | 2009-12-24 | — | — | US | disclosed |
| US-20080293676-A1 | Insecticidal Agents Based on Selected Insecticides and Safeners | BAYER CROPSCIENCE AG (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20070142327-A1 | Active compound combinations having insecticidal properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142327-A1 | Active compound combinations having insecticidal properties | ACHE, ANTXR2, NANP | TDP1 1655/4885MEN1 2606/4885KMT2A 2239/4885 |
| US-20160044921-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | ACHE, ACAT2, ACAT1 | TDP1 3994/4885MEN1 4379/4885KMT2A 3793/4885 |
| US-20090318386-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | AADAC, ACAA2, CYP51A1 | TDP1 4150/4885MEN1 3955/4885KMT2A 1284/4885 |
| US-20110124588-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | ACHE, ACAT2, ACAT1 | TDP1 3994/4885MEN1 4379/4885KMT2A 3793/4885 |
| US-20100249070-A1 | Active Compound Combinations Having Insecticidal Properties | ACHE, AADAC, NANP | TDP1 2009/4885MEN1 3378/4885KMT2A 1211/4885 |
| US-20140287915-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | ACHE, ACAT2, ACAT1 | TDP1 3994/4885MEN1 4379/4885KMT2A 3793/4885 |
| US-20120021901-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | ACHE, DDT, BCHE | TDP1 2269/4885MEN1 722/4885KMT2A 2325/4885 |
| US-20100311677-A1 | Active Ingredient Combinations Having Insecticidal and Acaricidal Properties | ACHE, ACAT2, ACAT1 | TDP1 3807/4885MEN1 3755/4885KMT2A 2847/4885 |
| US-20080293676-A1 | Insecticidal Agents Based on Selected Insecticides and Safeners | ACHE, NCS1, HCN1 | TDP1 3921/4885MEN1 2739/4885KMT2A 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.