Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15108863 | 0.83 | ALDH1A1 (0.39) | THRBTDP1MYCCYP3A4CYP2C9 | |
| SCHEMBL393095 | 0.83 | THRB (0.59) | THRBTDP1APEX1PDK2ALDH1A1 | |
| Bromide SCHEMBL27743787 | 0.81 | THRB (0.57) | THRBTDP1APEX1PDK2ALDH1A1 | |
| Bromomethane SCHEMBL209152 | 0.80 | THRB (0.55) | THRBTDP1APEX1PDK2ALDH1A1 | |
| SCHEMBL8094339 | 0.79 | THRB (0.67) | THRBTDP1MYCAPEX1PDK2 | |
| SCHEMBL6786858 | 0.76 | ALOX5 (0.38) | THRBTDP1MYCHTTHDAC4 | |
| SCHEMBL24933869 | 0.74 | PDK2 (0.41) | PDK2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| Propanol SCHEMBL27824438 | 0.72 | THRB (0.47) | THRBTDP1APEX1PDK2ALDH1A1 | |
| Nonane SCHEMBL27848744 | 0.72 | TDP1 (0.47) | THRBTDP1APEX1CYP2C9CYP2C19 | |
| SCHEMBL4577246 | 0.72 | PDK2 (0.47) | THRBTDP1MYCPDK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696462-B2 | CYCLOPROPYLTROPINE CARBOXYLATE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |
| US-20030207912-A1 | Anticholinergics, processes for the preparation thereof, and pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH. CO. KG (DE) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207912-A1 | Anticholinergics, processes for the preparation thereof, and pharmaceutical compositions | CHRM1, CHRNA1, CHRNB1 | THRB 1279/4885TDP1 3079/4885MYC 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.