Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | LAP3 | P28838 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24942191 | 0.94 | LTA4H (0.55) | LTA4HLAP3ALDH1A1POLBKMT2A | |
| Trifluoroacetic Acid SCHEMBL28278079 | 0.88 | ALPI (0.54) | LTA4HLAP3PTPN1ALDH1A1KMT2A | |
| SCHEMBL31177328 | 0.84 | PTPN1 (0.54) | LTA4HLAP3PTPN1ALDH1A1SLC15A1 | |
| SCHEMBL5222410 | 0.83 | LTA4H (0.55) | LTA4HLAP3ALDH1A1SLC15A1ALPI | |
| Trifluoroacetic Acid SCHEMBL28836301 | 0.83 | LTA4H (0.43) | LTA4HLAP3PTPN1ALDH1A1SLC15A1 | |
| Trifluoroacetic Acid SCHEMBL30098504 | 0.83 | LTA4H (0.43) | LTA4HLAP3PTPN1ALDH1A1SLC15A1 | |
| Trifluoroacetic Acid SCHEMBL30098486 | 0.83 | LTA4H (0.43) | LTA4HLAP3PTPN1ALDH1A1SLC15A1 | |
| Trifluoroacetic Acid SCHEMBL28836548 | 0.83 | LTA4H (0.43) | LTA4HLAP3PTPN1ALDH1A1SLC15A1 | |
| SCHEMBL15634364 | 0.82 | LTA4H (0.56) | LTA4HLAP3ALDH1A1SLC15A1ALPI | |
| SCHEMBL8907360 | 0.82 | LTA4H (0.56) | LTA4HLAP3ALDH1A1SLC15A1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006104-A1 | Neutrophil inhibitors to reduce inflammatory response | THE PROCTER & GAMBLE COMPANY | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006104-A1 | Neutrophil inhibitors to reduce inflammatory response | MPO, SERPINB1, NCF1 | LTA4H 125/4885LAP3 2958/4885PTPN1 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.