Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787397 | 0.82 | ADAM17 (0.39) | FFAR1PPARGPPARA | |
| SCHEMBL6786562 | 0.77 | HSP90AA1 (0.40) | HDAC2HDAC3HDAC1 | |
| SCHEMBL6784818 | 0.77 | ESR1 (0.42) | PPARA | |
| SCHEMBL6786095 | 0.77 | ESR1 (0.39) | HDAC2HDAC3HDAC1 | |
| SCHEMBL6785281 | 0.75 | ESR2 (0.40) | LTA4H | |
| SCHEMBL6785959 | 0.73 | KIF11 (0.39) | — | |
| SCHEMBL1062982 | 0.70 | LTA4H (0.57) | HDAC2ERN1LTA4H | |
| SCHEMBL28905907 | 0.69 | HDAC2 (0.47) | FFAR1HDAC2HDAC3HDAC1ERN1 | |
| SCHEMBL6785475 | 0.68 | KIF11 (0.38) | PPARGPPARA | |
| SCHEMBL7454111 | 0.68 | LTA4H (0.55) | HDAC2ERN1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825354-B2 | OSTEOPOROSIS; RHEUMATIC DISEASES | WYETH HOLDINGS CORPORATION | 2004-11-30 | — | — | US | disclosed |