Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | SELP | P16109 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835589 | 0.92 | SELP (0.53) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL8896628 | 0.92 | CNR1 (0.53) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL21559869 | 0.92 | NAAA (0.50) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL4103969 | 0.92 | SELP (0.56) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL11779596 | 0.90 | SELP (0.56) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL3832619 | 0.90 | SELP (0.56) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL11528832 | 0.90 | SELP (0.59) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL12565672 | 0.90 | SELP (0.59) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL21216091 | 0.90 | SELP (0.59) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL620134 | 0.90 | NAAA (0.54) | CNR1ALDH1A1MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147636-A1 | METHOD FOR PRODUCING N-METHYL-2-PYRROLIDONE USING POLYHYDROXYALKANOATE, AND N-METHYL-2-PYRROLIDONE PREPARED THEREFROM | 씨제이제일제당(주) | 2024-07-11 | — | — | WO | claimed |
| US-20120328536-A1 | Taste Improving Substances | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2012-12-27 | — | — | US | claimed |
| US-8067419-B2 | N-[(S)-1-benzyl-2-(4-benzyl-piperazin-1-yl)-2-oxo-ethyl]-N-(4-pentyl-benzyl)-3-(4-trifluoromethyl-phenyl)-acrylamide, for example; antiprotozoa agents | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-11-29 | — | — | US | claimed |
| US-8039644-B2 | Hydrogenated benzo (C) thiophene derivatives as immunomodulators | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-10-18 | — | — | US | claimed |
| EP-1863475-B1 | NOVEL THIOPHENE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE-1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-07 | — | — | EP | claimed |
| US-7951794-B2 | Thiophene derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-05-31 | — | — | US | claimed |
| EP-1863787-B1 | HYDOGRENATED BENZO[C]THIOPHENE DERIVATIVES AS IMMUNOMODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-05-25 | — | — | EP | claimed |
| US-7846964-B2 | Thiophene derivatives as spingosine-1-phosphate-1 receptor agonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-12-07 | — | — | US | claimed |
| US-20100204198-A1 | HYDROGENATED BENZO (C) THIOPHENE DERIVATIVES AS IMMUNOMODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2010-08-12 | — | — | US | claimed |
| US-7723378-B2 | G protein-coupled receptor S1P1/EDG1 agonists; 3-(4-hydroxy-3,5-dimethyl-phenyl)-1-(3,5,5-trimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)-propan-1-one; transplant rejection, graft-versus-host diseases, autoimmune syndromes; side effects reduction; immunosuppressive agents; Crohn's disease | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-05-25 | — | — | US | claimed |
| US-20060287207-A1 | Composition for removing a photoresist, method of preparing the composition, method of removing a photoresist and method of manufacturing a semiconductor device using the composition | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2006-12-21 | — | — | US | claimed |
| WO-2006100631-A1 | HYDROGENATED BENZO (C) THIOPHENE DERIVATIVES AS IMMUNOMODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-09-28 | — | — | WO | claimed |
| WO-2006100633-A1 | NOVEL THIOPHENE DERIVATIVES AS SPHINGOSINE-l-PHOSPHATE-1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-09-28 | — | — | WO | claimed |
| WO-2006100635-A2 | NOVEL THIOPHENE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE-1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-09-28 | — | — | WO | claimed |
| US-20030144551-A1 | Methods of making intermediates from polyhydroxyalkanoates | CJ CHEILJEDANG CORPORATION (KR) | 2003-07-31 | — | — | US | claimed |
| WO-2003051813-A1 | METHODS OF MAKING INTERMEDIATES FROM POLYHYDROXYALKANOATES | METABOLIX, INC. (US) | 2003-06-26 | — | — | WO | claimed |
| US-5753708-A | Derivatives of 4-hydroxybutyric acid | KOEHLER GERNOT (DE) | 1998-05-19 | — | — | US | claimed |
| EP-0536369-A1 | 4-HYDROXY BUTYRIC ACID DERIVATIVES. | KOEHLER CHEMIE DR FRANZ (DE) | 1993-04-14 | — | — | EP | claimed |
| WO-1992019581-A1 | 4-HYDROXY BUTYRIC ACID DERIVATIVES | Dr. Franz Köhler Chemie GmbH (DE) | 1992-11-12 | — | — | WO | claimed |
| US-4143159-A | SKIN-CARE AGENTS CONTAINING HYDROXYALKYL CARBOXAMIDES AND PROCESS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-03-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204198-A1 | HYDROGENATED BENZO (C) THIOPHENE DERIVATIVES AS IMMUNOMODULATORS | NFATC1, ICOS, TPMT | CNR1 469/4885ALDH1A1 867/4885MEN1 4419/4885 |
| US-20120328536-A1 | Taste Improving Substances | TAS2R5, TAS2R3, TAS2R42 | CNR1 742/4885ALDH1A1 568/4885MEN1 3716/4885 |
| US-20030144551-A1 | Methods of making intermediates from polyhydroxyalkanoates | HMBS, COASY, PGLS | CNR1 4377/4885ALDH1A1 1161/4885MEN1 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.