Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548120 | 0.79 | MEN1 (0.49) | LMNAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28548118 | 0.79 | MEN1 (0.49) | LMNAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2950945 | 0.75 | FKBP1A (0.50) | LMNAALDH1A1FKBP1ARAB9ANPC1 | |
| SCHEMBL6790854 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1FKBP1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6790851 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1FKBP1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6792263 | 0.73 | MTNR1A (0.38) | ALDH1A1RAB9ANPC1HTTMEN1 | |
| SCHEMBL6792267 | 0.73 | MTNR1A (0.38) | ALDH1A1RAB9ANPC1HTTMEN1 | |
| SCHEMBL22409405 | 0.71 | ALDH1A1 (0.39) | ALDH1A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL2950930 | 0.71 | FKBP1A (0.47) | LMNAALDH1A1FKBP1ARAB9ANPC1 | |
| SCHEMBL6987291 | 0.70 | MTNR1A (0.42) | LMNAALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720338-B2 | BCL-X1 INHIBITING COMPOSITIONS AND METHODS OF PROMOTING APOPTOSIS IN A MAMMAL | ABBOTT LABORATORIES | 2004-04-13 | — | — | US | disclosed |