Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 12/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792786 | 0.91 | KMT2A (0.44) | ALDH1A1LTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6796239 | 0.89 | GAA (0.55) | ALDH1A1LTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6794768 | 0.84 | RAB9A (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2ADRB1 | |
| SCHEMBL6501858 | 0.83 | GCGR (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2LIMK1 | |
| SCHEMBL6491092 | 0.82 | CYP3A4 (0.38) | ALDH1A1NPC1RAB9ALIMK1POLB | |
| SCHEMBL6794781 | 0.82 | RAB9A (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPK13 | |
| SCHEMBL6788594 | 0.80 | NPC1 (0.43) | ALDH1A1LTB4R2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6793528 | 0.79 | NR3C1 (0.41) | ALDH1A1LTB4R2NPC1LIMK1CHRNB2 | |
| SCHEMBL6503623 | 0.79 | MTTP (0.40) | NPC1RAB9ALIMK1 | |
| SCHEMBL6788065 | 0.78 | SMO (0.42) | SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | ALDH1A1 1427/4885LTB4R2 242/4885NPC1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.