SCHEMBL6796239

SCHEMBL6796239

COc1ccc(-c2ccccc2C(=O)Nc2ccc(N(CCc3cscn3)C(=O)O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.55
POLB P06746 1/20 0.55
LTB4R2 Q9NPC1 1/20 0.44
MEN1 O00255 7/20 0.44
KMT2A Q03164 7/20 0.44
MAPT P10636 5/20 0.44
ALDH1A1 P00352 4/20 0.43
RAB9A P51151 3/20 0.43
MAPK1 P28482 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
PKM P14618 1/20 0.42
CYP3A4 P08684 3/20 0.42
TSHR P16473 2/20 0.41
USP2 O75604 1/20 0.41
RECQL P46063 1/20 0.41
LPAR1 Q92633 1/20 0.41
PPARG P37231 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6792786 0.91 KMT2A (0.44) GAAPOLBLTB4R2MEN1KMT2A
SCHEMBL6792292 0.89 ALDH1A1 (0.41) GAAPOLBLTB4R2MAPTALDH1A1
SCHEMBL6788603 0.84 GAA (0.58) GAAPOLBMEN1KMT2AMAPT
SCHEMBL6501858 0.82 GCGR (0.43) POLBMEN1KMT2AALDH1A1RAB9A
SCHEMBL6491092 0.82 CYP3A4 (0.38) POLBMEN1KMT2AMAPTALDH1A1
SCHEMBL6793968 0.81 GAA (0.48) GAAPOLBLTB4R2MEN1KMT2A
SCHEMBL6793528 0.80 NR3C1 (0.41) GAAPOLBLTB4R2MEN1KMT2A
SCHEMBL6788065 0.79 SMO (0.42) GAAKDM4ESMN1; SMN2
SCHEMBL6503623 0.79 MTTP (0.40) RAB9AKDM4ENPC1CYP3A4
SCHEMBL6788433 0.79 GAA (0.49) GAAPOLBLTB4R2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 GAA 977/4885POLB 1470/4885LTB4R2 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.