Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501746 | 0.87 | HDAC1 (0.37) | MAPTRAB9AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL6489918 | 0.83 | ALDH1A1 (0.43) | MAPTRAB9AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL6795253 | 0.80 | ALDH1A1 (0.39) | MAPTRAB9AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL6489438 | 0.77 | POLB (0.51) | RAB9AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL6794742 | 0.75 | MEN1 (0.40) | MAPTRAB9APAX8GAAMEN1 | |
| SCHEMBL27583338 | 0.74 | GSTO1 (0.35) | HDAC1HDAC6 | |
| SCHEMBL6500907 | 0.74 | MMP1 (0.39) | MAPTRAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27678360 | 0.74 | ALDH1A1 (0.44) | MAPTRAB9AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL380709 | 0.73 | ALDH1A1 (0.57) | MAPTALDH1A1SMN1; SMN2PAX8CYP1A2 | |
| SCHEMBL6081269 | 0.73 | ALDH1A1 (0.57) | MAPTRAB9AALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | MAPT 4795/4885RAB9A 3707/4885HDAC1 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.