SCHEMBL6793928

SCHEMBL6793928

CCc1nc2c(N=C=S)c(F)cc(Cl)c2o1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
PDE7B Q9NP56 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6794232 0.76 FBP1 (0.35) PDE7B
SCHEMBL6658600 0.71 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL6788315 0.70 ALDH1A1 (0.36) PDE7B
SCHEMBL9149540 0.66 ALDH1A1 (0.31)
SCHEMBL6794737 0.64 PDE7B (0.41) PDE7B
SCHEMBL17200648 0.62 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL11555693 0.61 GABRA1 (0.36) GABRA1GABRB2
SCHEMBL23511003 0.61 GABRA1 (0.41) GABRA1GABRB2
SCHEMBL23510913 0.61 GABRA1 (0.41) GABRA1GABRB2
SCHEMBL17650908 0.61 GABRA1 (0.33) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040029734-A1 Fused-benzene derivatives useful as herbicides ISHIHARA SANGYO KAISHA, LTD. 2004-02-12 US disclosed
US-6573218-B1 Defoliants containing such as uracil and 1,4-benzoxazole or benzthiazole moieties ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-06-03 US disclosed
EP-1111993-A4 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA (JP) 2002-12-04 EP disclosed
EP-1111993-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-07-04 EP disclosed
WO-2000013508-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029734-A1 Fused-benzene derivatives useful as herbicides DDT, NQO2, DHRS9 GABRA1 1384/4885GABRB2 446/4885PDE7B 4125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.